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Package description

GenomAutomorphism
GenomAutomorphism: An R package to compute the automorphisms between DNA sequences represented as elements from an Abelian group.

Codon and DNA Base Algebraic Representation

codon_coord()
Codon coordinates on a given a given Abelian group representation.
base_coord()
Base coordinates on a given a given Abelian group representation.
get_coord()
DNA base/codon sequence and coordinates represented on a given Abelian group.
matrices()
Get the Coordinate Representation from DNA Sequences on Specified Abelian Group
seqranges()
Get DNA sequence Ranges and Coordinates representation on a given Abelian Group

Automorphisms

automorphisms()
Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in a Given Abelian group.
autZ5()
Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z5.
autZ64()
Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z64.
autZ125()
Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z125.
aut3D()
Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z5^3.

Automorphisms methods

automorphismByRanges()
Get the automorphisms by ranges.
automorphism_bycoef()
Autmorphism Grouping by Coefficient
getAutomorphisms()
Get Automorphisms
conserved_regions()
Conserved and Non-conserved Regions from a MSA
as.AutomorphismList()
Methods for AutomorphismList-class Objects
mut_type()
Classification of DNA base mutations

Distance functions

codon_dist()
Weighted Manhattan Distance Between Codons
codon_dist_matrix()
Compute Codon Distance Matrix
aminoacid_dist()
Distance Between Aminoacids in Terms of Codon Distance

Utils

base2codon()
Split a DNA sequence into codons
base2int()
Replace bases with integers from Z4 and Z5
sortByChromAndStart() sortByChromAndEnd()
Sorting GRanges-class objects
slapply()
Apply a function over a list-like object preserving its attributes
aa_mutmat()
Amino acid mutation matrix
get_mutscore()
Get Mutation Score from an AAindex Matrix
str2chr()
String to Character
str2dig()
String to Digits
translation()
Translation of DNA/RNA sequences

Data sets

aln
Simulated DNAStringSet class object
autm
Automorphisms between DNA Sequences from two COVID-19 genomes
cyc_aln
Multiple Sequence Alignment (MSA) of Primate Somatic Cytochrome C
autm_3d
Automorphisms between DNA Sequences from two COVID-19 genomes
autm_z125
Automorphisms between DNA Sequences from two COVID-19 genomes
cyc_autm
Automorphisms between DNA Sequences from Primate Cytochrome C Genes
autby_coef
Automorphisms between DNA Primate BRCA1 Genes Grouped by Coefficients
covid_aln
Pairwise Sequence Alignment (MSA) of COVID-19 genomes.
covid_autm
Automorphisms between DNA Sequences from two COVID-19 genomes
brca1_aln
Multiple Sequence Alignment (MSA) of Primate BRCA1 DNA repair genes.
brca1_aln2
Multiple Sequence Alignment (MSA) of Primate BRCA1 DNA repair genes.
brca1_autm
Automorphisms between DNA Sequences from Primate BRCA1 Genes
brca1_autm2
Automorphisms between DNA Sequences from Primate BRCA1 Genes
aaindex2
List of 94 Amino Acid Matrices from AAindex
aaindex3
Statistical protein contact potentials matrices from AAindex ver.9.2